Ccn6 - cellular communication network factor 6

Predicted to enable heparin binding activity and integrin binding activity. Predicted to be involved in several processes, including negative regulation of cell death; regulation of mitochondrial membrane potential; and regulation of reactive oxygen species biosynthetic process. Predicted to act upstream of or within negative regulation of angiogenesis and negative regulation of cell population proliferation. Predicted to be located in extracellular space and mitochondrion. Predicted to be active in extracellular matrix. Is expressed in embryo. Used to study breast metaplastic carcinoma and progressive pseudorheumatoid arthropathy of childhood. Human ortholog(s) of this gene implicated in progressive pseudorheumatoid arthropathy of childhood. Orthologous to human CCN6 (cellular communication network factor 6). [provided by Alliance of Genome Resources, Apr 2022]