Predicted to enable identical protein binding activity and serine-type endopeptidase activity. Predicted to be involved in complement activation, classical pathway and proteolysis. Predicted to act upstream of or within innate immune response. Predicted to be located in extracellular region. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in Ehlers-Danlos syndrome periodontal type 2. Orthologous to human C1S (complement C1s). [provided by Alliance of Genome Resources, Apr 2022]