Porcn - porcupine O-acyltransferase

Predicted to enable Wnt-protein binding activity and palmitoleoyltransferase activity. Predicted to be involved in several processes, including Wnt protein secretion; protein lipidation; and regulation of postsynaptic membrane neurotransmitter receptor levels. Predicted to act upstream of or within glycoprotein metabolic process. Predicted to be integral component of endoplasmic reticulum membrane. Predicted to be part of AMPA glutamate receptor complex. Predicted to be active in endoplasmic reticulum; glutamatergic synapse; and membrane. Human ortholog(s) of this gene implicated in focal dermal hypoplasia. Orthologous to human PORCN (porcupine O-acyltransferase). [provided by Alliance of Genome Resources, Apr 2022]