Bcor - BCL6 co-repressor

Predicted to enable several functions, including heat shock protein binding activity; histone deacetylase binding activity; and transcription corepressor activity. Predicted to contribute to ubiquitin-protein transferase activity. Predicted to be involved in several processes, including histone H2A monoubiquitination; negative regulation of biomineral tissue development; and negative regulation of histone methylation. Predicted to act upstream of or within blastocyst hatching and negative regulation of transcription by RNA polymerase II. Predicted to be located in nucleoplasm. Predicted to be part of BCOR complex. Human ortholog(s) of this gene implicated in colorectal cancer; stomach cancer; stomach carcinoma; syndromic microphthalmia 1; and syndromic microphthalmia 2. Orthologous to human BCOR (BCL6 corepressor). [provided by Alliance of Genome Resources, Apr 2022]