Taf1 - TATA-box binding protein associated factor 1

Predicted to enable several functions, including RNA polymerase I general transcription initiation factor activity; RNA polymerase II core promoter sequence-specific DNA binding activity; and RNA polymerase II general transcription initiation factor activity. Predicted to contribute to H3K27me3 modified histone binding activity. Involved in response to xenobiotic stimulus. Located in nucleus. Human ortholog(s) of this gene implicated in X-linked dystonia-parkinsonism and syndromic X-linked intellectual disability. Orthologous to human TAF1 (TATA-box binding protein associated factor 1). [provided by Alliance of Genome Resources, Apr 2022]