Predicted to enable heparan sulfate 6-O-sulfotransferase activity. Predicted to be involved in heparan sulfate proteoglycan biosynthetic process, enzymatic modification and neuron development. Predicted to act upstream of or within blood vessel development; heparan sulfate proteoglycan biosynthetic process; and lung alveolus development. Predicted to be integral component of membrane. Human ortholog(s) of this gene implicated in hypogonadotropic hypogonadism 15 with or without anosmia. Orthologous to human HS6ST1 (heparan sulfate 6-O-sulfotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]