Cd2ap - CD2-associated protein

Enables several functions, including beta-catenin binding activity; cadherin binding activity; and protein C-terminus binding activity. Involved in several processes, including cell-cell adhesion; proteasome-mediated ubiquitin-dependent protein catabolic process; and regulation of receptor-mediated endocytosis. Located in cell leading edge; endocytic vesicle; and perinuclear region of cytoplasm. Part of protein-containing complex. Human ortholog(s) of this gene implicated in focal segmental glomerulosclerosis and focal segmental glomerulosclerosis 3. Orthologous to human CD2AP (CD2 associated protein). [provided by Alliance of Genome Resources, Apr 2022]