Uaca - uveal autoantigen with coiled-coil domains and ankyrin repeats

Predicted to be involved in negative regulation of NIK/NF-kappaB signaling and positive regulation of cysteine-type endopeptidase activity involved in apoptotic process. Predicted to act upstream of or within several processes, including intrinsic apoptotic signaling pathway; negative regulation of inflammatory response; and positive regulation of protein import into nucleus. Predicted to be located in membrane; nucleus; and perinuclear region of cytoplasm. Predicted to be part of apoptosome. Predicted to be active in cytosol and nucleus. Orthologous to human UACA (uveal autoantigen with coiled-coil domains and ankyrin repeats). [provided by Alliance of Genome Resources, Apr 2022]