Csk - C-terminal Src kinase

Enables proline-rich region binding activity; protein phosphatase binding activity; and protein tyrosine kinase activity. Involved in several processes, including central nervous system development; negative regulation of bone resorption; and regulation of MAPK cascade. Located in cytoplasm and membrane raft. Biomarker of hepatocellular carcinoma. Orthologous to human CSK (C-terminal Src kinase). [provided by Alliance of Genome Resources, Apr 2022]