Jam3 - junctional adhesion molecule 3

Predicted to enable cell-cell adhesion mediator activity; identical protein binding activity; and integrin binding activity. Involved in axon regeneration. Predicted to be located in several cellular components, including Schmidt-Lanterman incisure; cell-cell contact zone; and paranodal junction. Predicted to be integral component of plasma membrane. Predicted to be part of filamentous actin and protein complex involved in cell adhesion. Predicted to colocalize with bicellular tight junction. Biomarker of sciatic neuropathy. Orthologous to human JAM3 (junctional adhesion molecule 3). [provided by Alliance of Genome Resources, Apr 2022]