Irak3 - interleukin-1 receptor-associated kinase 3

Predicted to enable several functions, including ATP binding activity; magnesium ion binding activity; and protein dimerization activity. Predicted to be involved in several processes, including negative regulation of protein metabolic process; regulation of gene expression; and response to bacterium. Predicted to act upstream of or within protein autophosphorylation. Predicted to be active in cytoplasm; nucleus; and plasma membrane. Human ortholog(s) of this gene implicated in asthma. Orthologous to human IRAK3 (interleukin 1 receptor associated kinase 3). [provided by Alliance of Genome Resources, Apr 2022]