Cep290 - centrosomal protein 290

Predicted to enable identical protein binding activity. Predicted to be involved in several processes, including animal organ development; cilium assembly; and positive regulation of intracellular protein transport. Predicted to act upstream of or within several processes, including animal organ development; determination of left/right symmetry; and photoreceptor cell maintenance. Located in ciliary basal body. Human ortholog(s) of this gene implicated in Bardet-Biedl syndrome 14; Joubert syndrome 5; Leber congenital amaurosis 10; Meckel syndrome 4; and Senior-Loken syndrome. Orthologous to human CEP290 (centrosomal protein 290). [provided by Alliance of Genome Resources, Apr 2022]