Pip5k1c - phosphatidylinositol-4-phosphate 5-kinase type 1 gamma

Predicted to enable 1-phosphatidylinositol-4-phosphate 5-kinase activity and talin binding activity. Predicted to be involved in regulation of postsynaptic neurotransmitter receptor internalization and regulation of synaptic vesicle endocytosis. Predicted to act upstream of or within axonogenesis; phosphatidylinositol biosynthetic process; and platelet aggregation. Is active in presynaptic endocytic zone membrane. Human ortholog(s) of this gene implicated in lethal congenital contracture syndrome 3. Orthologous to human PIP5K1C (phosphatidylinositol-4-phosphate 5-kinase type 1 gamma). [provided by Alliance of Genome Resources, Apr 2022]