Dync2i1 - dynein 2 intermediate chain 1

Predicted to enable dynein heavy chain binding activity and dynein light chain binding activity. Predicted to be involved in cilium assembly; embryonic skeletal system morphogenesis; and intraciliary retrograde transport. Predicted to be located in cilium and pericentriolar material. Predicted to be part of cytoplasmic dynein complex. Predicted to be active in ciliary plasm. Predicted to colocalize with ciliary base and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in short-rib thoracic dysplasia 8 with or without polydactyly. Orthologous to human DYNC2I1 (dynein 2 intermediate chain 1). [provided by Alliance of Genome Resources, Apr 2022]