Bcl11b - BCL11 transcription factor B

Predicted to enable DNA-binding transcription activator activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in hematopoietic stem cell migration; lymphoid lineage cell migration into thymus; and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including animal organ development; cell morphogenesis involved in differentiation; and regulation of keratinocyte proliferation. Predicted to be located in neuron projection. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in immunodeficiency 49. Orthologous to human BCL11B (BAF chromatin remodeling complex subunit BCL11B). [provided by Alliance of Genome Resources, Apr 2022]