Clec14a - C-type lectin domain containing 14A

Predicted to enable extracellular matrix binding activity and extracellular matrix protein binding activity. Predicted to be involved in cell migration involved in sprouting angiogenesis. Predicted to act upstream of or within with a positive effect on vascular endothelial growth factor receptor-3 signaling pathway. Predicted to act upstream of or within with a negative effect on vascular endothelial growth factor receptor-2 signaling pathway. Predicted to act upstream of or within lymphangiogenesis and sprouting angiogenesis. Predicted to be integral component of membrane. Predicted to be active in external side of plasma membrane. Orthologous to human CLEC14A (C-type lectin domain containing 14A). [provided by Alliance of Genome Resources, Apr 2022]