Grhl1 - grainyhead-like transcription factor 1

Predicted to enable DNA binding activity; DNA-binding transcription activator activity, RNA polymerase II-specific; and protein homodimerization activity. Predicted to be involved in epidermis development and positive regulation of transcription by RNA polymerase II. Predicted to act upstream of or within desmosome organization; establishment of skin barrier; and regulation of keratinocyte differentiation. Predicted to be located in nucleoplasm. Orthologous to human GRHL1 (grainyhead like transcription factor 1). [provided by Alliance of Genome Resources, Apr 2022]