Predicted to enable ubiquitin binding activity; ubiquitin conjugating enzyme binding activity; and ubiquitin protein ligase activity. Predicted to be involved in positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein ubiquitination; and ubiquitin-dependent protein catabolic process. Predicted to act upstream of or within natural killer cell mediated cytotoxicity. Predicted to be located in cytosol and endoplasmic reticulum. Predicted to be part of ubiquitin ligase complex. Predicted to be active in cytolytic granule. Orthologous to human RNF19B (ring finger protein 19B). [provided by Alliance of Genome Resources, Apr 2022]