Ago3 - argonaute RISC catalytic component 3

Predicted to enable RNA binding activity and endoribonuclease activity, cleaving miRNA-paired mRNA. Predicted to be involved in several processes, including RNA metabolic process; gene silencing by miRNA; and positive regulation of NIK/NF-kappaB signaling. Predicted to be located in cytoplasmic ribonucleoprotein granule; cytosol; and nuclear lumen. Predicted to be part of RISC complex and RISC-loading complex. Orthologous to human AGO3 (argonaute RISC catalytic component 3). [provided by Alliance of Genome Resources, Apr 2022]