Bach2 - BTB domain and CNC homolog 2

Predicted to enable DNA-binding transcription repressor activity, RNA polymerase II-specific and RNA polymerase II cis-regulatory region sequence-specific DNA binding activity. Predicted to be involved in import into nucleus; negative regulation of transcription by RNA polymerase II; and primary adaptive immune response involving T cells and B cells. Predicted to act upstream of or within regulation of transcription, DNA-templated. Predicted to be located in cytosol and nucleoplasm. Human ortholog(s) of this gene implicated in immunodeficiency 60. Orthologous to human BACH2 (BTB domain and CNC homolog 2). [provided by Alliance of Genome Resources, Apr 2022]