Enables ATP binding activity and MAP kinase kinase kinase activity. Involved in MAPK cascade; positive regulation of intracellular signal transduction; and protein phosphorylation. Predicted to be located in cytosol; plasma membrane; and postsynaptic density. Human ortholog(s) of this gene implicated in frontometaphyseal dysplasia 2 and prostate cancer. Orthologous to human MAP3K7 (mitogen-activated protein kinase kinase kinase 7). [provided by Alliance of Genome Resources, Apr 2022]