Trpa1 - transient receptor potential cation channel, subfamily A, member 1

Enables osmolarity-sensing cation channel activity and voltage-gated calcium channel activity. Involved in several processes, including cellular response to caffeine; positive regulation of transport; and regulation of nervous system process. Located in apical plasma membrane and axon. Used to study asthma and diabetic neuropathy. Human ortholog(s) of this gene implicated in familial episodic pain syndrome 1. Orthologous to human TRPA1 (transient receptor potential cation channel subfamily A member 1). [provided by Alliance of Genome Resources, Apr 2022]