Eps8 - epidermal growth factor receptor pathway substrate 8

Predicted to enable actin binding activity and small GTPase binding activity. Predicted to be involved in several processes, including Ras protein signal transduction; actin filament organization; and barbed-end actin filament capping. Predicted to act upstream of or within several processes, including actin cytoskeleton reorganization; behavioral response to ethanol; and cellular response to leukemia inhibitory factor. Is active in glutamatergic synapse and postsynaptic density. Human ortholog(s) of this gene implicated in autosomal recessive nonsyndromic deafness 102. Orthologous to human EPS8 (epidermal growth factor receptor pathway substrate 8). [provided by Alliance of Genome Resources, Apr 2022]