Etv6 - ETS variant transcription factor 6

Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific; RNA polymerase II cis-regulatory region sequence-specific DNA binding activity; and protein domain specific binding activity. Predicted to be involved in cell differentiation; hematopoietic stem cell proliferation; and regulation of transcription by RNA polymerase II. Predicted to act upstream of or within several processes, including mesenchymal cell apoptotic process; regulation of transcription, DNA-templated; and vitellogenesis. Predicted to be located in cytosol and nucleolus. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in hematologic cancer (multiple) and thrombocytopenia. Orthologous to human ETV6 (ETS variant transcription factor 6). [provided by Alliance of Genome Resources, Apr 2022]