Pex5 - peroxisomal biogenesis factor 5

Predicted to enable several functions, including peroxisome targeting sequence binding activity; protein C-terminus binding activity; and protein sequestering activity. Predicted to be involved in negative regulation of protein-containing complex assembly; protein targeting to peroxisome; and protein tetramerization. Predicted to act upstream of or within several processes, including fatty acid metabolic process; mitochondrial membrane organization; and nervous system development. Located in cytosol and peroxisomal membrane. Part of protein-containing complex. Human ortholog(s) of this gene implicated in peroxisome biogenesis disorder 2A; peroxisome biogenesis disorder 2B; and rhizomelic chondrodysplasia punctata type 5. Orthologous to human PEX5 (peroxisomal biogenesis factor 5). [provided by Alliance of Genome Resources, Apr 2022]