Marchf8 - membrane associated ring-CH-type finger 8

Predicted to enable MHC class II protein binding activity and ubiquitin protein ligase activity. Predicted to be involved in several processes, including antigen processing and presentation of peptide antigen via MHC class II; negative regulation of MHC class II biosynthetic process; and protein polyubiquitination. Predicted to be located in endosome. Predicted to be active in early endosome membrane; late endosome membrane; and lysosome. Orthologous to human MARCHF8 (membrane associated ring-CH-type finger 8). [provided by Alliance of Genome Resources, Apr 2022]