Fancd2 - FA complementation group D2

Predicted to enable DNA polymerase binding activity. Predicted to be involved in several processes, including interstrand cross-link repair; meiosis I; and mitotic intra-S DNA damage checkpoint signaling. Predicted to act upstream of or within several processes, including neuronal stem cell population maintenance; regulation of CD40 signaling pathway; and regulation of regulatory T cell differentiation. Predicted to be located in cytosol; nuclear body; and nucleolus. Predicted to be active in condensed chromosome and nucleus. Human ortholog(s) of this gene implicated in Fanconi anemia; Fanconi anemia complementation group D2; and breast cancer. Orthologous to human FANCD2 (FA complementation group D2). [provided by Alliance of Genome Resources, Apr 2022]