Dennd1a - DENN domain containing 1A

Predicted to enable several functions, including SH3 domain binding activity; guanyl-nucleotide exchange factor activity; and phosphatidylinositol-3-phosphate binding activity. Predicted to be involved in several processes, including endocytic recycling; positive regulation of GTPase activity; and regulation of Rab protein signal transduction. Predicted to act upstream of or within synaptic vesicle endocytosis. Predicted to be located in several cellular components, including clathrin-coated vesicle membrane; dendrite; and neuronal cell body. Predicted to be active in clathrin-coated vesicle and cytosol. Orthologous to human DENND1A (DENN domain containing 1A). [provided by Alliance of Genome Resources, Apr 2022]