Lrrc8a - leucine rich repeat containing 8 VRAC subunit A
Alias:
Lrrc8
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Description
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
Interactions
Related Mouse Models
References Literature
Enables volume-sensitive anion channel activity. Involved in aspartate transmembrane transport; response to osmotic stress; and taurine transport. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in agammaglobulinemia and agammaglobulinemia 5. Orthologous to human LRRC8A (leucine rich repeat containing 8 VRAC subunit A). [provided by Alliance of Genome Resources, Apr 2022]