Il36rn - interleukin 36 receptor antagonist

Predicted to enable cytokine activity; interleukin-1 receptor antagonist activity; and interleukin-1 receptor binding activity. Predicted to be involved in several processes, including antifungal humoral response; cellular response to lipopolysaccharide; and negative regulation of cytokine production. Predicted to act upstream of or within negative regulation of interleukin-6 production. Predicted to be active in extracellular space. Human ortholog(s) of this gene implicated in pustular psoriasis 14. Orthologous to human IL36RN (interleukin 36 receptor antagonist). [provided by Alliance of Genome Resources, Apr 2022]