Map3k20 - mitogen-activated protein kinase kinase kinase 20

Predicted to enable ATP binding activity; MAP kinase kinase kinase activity; and magnesium ion binding activity. Predicted to be involved in several processes, including cellular response to gamma radiation; intracellular signal transduction; and positive regulation of mitotic DNA damage checkpoint. Predicted to act upstream of or within cytoskeleton organization and embryonic digit morphogenesis. Predicted to be located in cytosol and nucleus. Predicted to be active in cytoplasm. Human ortholog(s) of this gene implicated in centronuclear myopathy 6 with fiber-type disproportion. Orthologous to human MAP3K20 (mitogen-activated protein kinase kinase kinase 20). [provided by Alliance of Genome Resources, Apr 2022]