Bmpr1b - bone morphogenetic protein receptor type 1B

Predicted to enable several functions, including ATP binding activity; enzyme activator activity; and transmembrane receptor protein serine/threonine kinase activity. Predicted to be involved in several processes, including ovarian cumulus expansion; positive regulation of bone mineralization; and positive regulation of osteoblast differentiation. Predicted to act upstream of or within several processes, including cartilage development; positive regulation of extrinsic apoptotic signaling pathway via death domain receptors; and retinal ganglion cell axon guidance. Located in dendrite and neuronal cell body. Human ortholog(s) of this gene implicated in brachydactyly type A1D; brachydactyly type A2; and osteochondrodysplasia. Orthologous to human BMPR1B (bone morphogenetic protein receptor type 1B). [provided by Alliance of Genome Resources, Apr 2022]