Tet2 - tet methylcytosine dioxygenase 2

Predicted to enable ferrous iron binding activity; methylcytosine dioxygenase activity; and zinc ion binding activity. Involved in response to organic cyclic compound. Predicted to be active in nucleus. Human ortholog(s) of this gene implicated in gastrointestinal system cancer (multiple); hematologic cancer (multiple); lung non-small cell carcinoma; and primary immunodeficiency disease. Orthologous to human TET2 (tet methylcytosine dioxygenase 2). [provided by Alliance of Genome Resources, Apr 2022]