Sgms2 - sphingomyelin synthase 2

Predicted to enable ceramide cholinephosphotransferase activity; ceramide phosphoethanolamine synthase activity; and sphingomyelin synthase activity. Predicted to be involved in ceramide biosynthetic process; regulation of bone mineralization; and sphingomyelin biosynthetic process. Predicted to act upstream of or within ceramide phosphoethanolamine biosynthetic process. Is integral component of plasma membrane. Human ortholog(s) of this gene implicated in calvarial doughnut lesions with bone fragility. Orthologous to human SGMS2 (sphingomyelin synthase 2). [provided by Alliance of Genome Resources, Apr 2022]