Lrig2 - leucine-rich repeats and immunoglobulin-like domains 2

Predicted to enable signaling receptor binding activity. Predicted to act upstream of or within several processes, including negative regulation of axon regeneration; negative regulation of membrane protein ectodomain proteolysis; and positive regulation of protein localization to cell surface. Predicted to be located in several cellular components, including growth cone; intracellular vesicle; and neuronal cell body. Predicted to be active in extracellular matrix and extracellular space. Human ortholog(s) of this gene implicated in urofacial syndrome. Orthologous to human LRIG2 (leucine rich repeats and immunoglobulin like domains 2). [provided by Alliance of Genome Resources, Apr 2022]