Otud7b - OTU deubiquitinase 7B

Predicted to enable K63-linked polyubiquitin modification-dependent protein binding activity; Lys48-specific deubiquitinase activity; and thiol-dependent deubiquitinase. Predicted to be involved in several processes, including negative regulation of I-kappaB kinase/NF-kappaB signaling; negative regulation of macromolecule metabolic process; and protein deubiquitination. Predicted to act upstream of or within in utero embryonic development and protein deubiquitination. Predicted to be active in cytoplasm and nucleus. Orthologous to human OTUD7B (OTU deubiquitinase 7B). [provided by Alliance of Genome Resources, Apr 2022]