Rapgef2 - Rap guanine nucleotide exchange factor 2

Enables protein kinase binding activity. Involved in several processes, including cell surface receptor signaling pathway; positive regulation of ERK1 and ERK2 cascade; and positive regulation of GTPase activity. Located in several cellular components, including neuron projection; neuronal cell body; and synapse. Part of protein-containing complex. Human ortholog(s) of this gene implicated in familial adult myoclonic epilepsy 7. Orthologous to human RAPGEF2 (Rap guanine nucleotide exchange factor 2). [provided by Alliance of Genome Resources, Apr 2022]