Frem2 - FRAS1 related extracellular matrix 2

Predicted to be involved in cell adhesion. Predicted to act upstream of or within animal organ development; embryonic digit morphogenesis; and morphogenesis of an epithelium. Predicted to be located in basement membrane. Used to study Fraser syndrome 2. Human ortholog(s) of this gene implicated in Fraser syndrome 2 and isolated cryptophthalmia. Orthologous to human FREM2 (FRAS1 related extracellular matrix 2). [provided by Alliance of Genome Resources, Apr 2022]