Trio - trio Rho guanine nucleotide exchange factor

Enables enzyme binding activity. Predicted to be involved in axon guidance and negative regulation of fat cell differentiation. Predicted to be located in cell projection. Predicted to be active in cytoplasm. Predicted to be extrinsic component of membrane. Human ortholog(s) of this gene implicated in autosomal dominant non-syndromic intellectual disability and autosomal dominant non-syndromic intellectual disability 44. Orthologous to human TRIO (trio Rho guanine nucleotide exchange factor). [provided by Alliance of Genome Resources, Apr 2022]