Predicted to enable beta-3 adrenergic receptor binding activity. Predicted to be involved in negative regulation of cold-induced thermogenesis and protein transport. Predicted to act upstream of or within several processes, including fat pad development; negative regulation of locomotion involved in locomotory behavior; and positive regulation of ubiquitin-protein transferase activity. Predicted to be located in early endosome and lysosome. Predicted to be active in endosome and plasma membrane. Orthologous to human ARRDC3 (arrestin domain containing 3). [provided by Alliance of Genome Resources, Apr 2022]