Itgb2 - integrin subunit beta 2

Contributes to cell adhesion molecule binding activity. Involved in several processes, including leukocyte migration; positive regulation of angiogenesis; and regulation of cellular biosynthetic process. Located in cell surface and plasma membrane. Used to study nephritis and pneumonia. Biomarker of allergic rhinitis. Human ortholog(s) of this gene implicated in coronary restenosis; leukocyte adhesion deficiency; and leukocyte adhesion deficiency 1. Orthologous to human ITGB2 (integrin subunit beta 2). [provided by Alliance of Genome Resources, Apr 2022]