Hps6 - HPS6, biogenesis of lysosomal organelles complex 2 subunit 3

Predicted to enable GTP-dependent protein binding activity and small GTPase binding activity. Predicted to be involved in several processes, including lysosome localization; melanocyte differentiation; and protein secretion. Predicted to act upstream of or within blood coagulation and pigmentation. Predicted to be located in early endosome membrane and endoplasmic reticulum. Predicted to be part of BLOC-2 complex. Predicted to be active in lysosomal membrane. Human ortholog(s) of this gene implicated in Hermansky-Pudlak syndrome and Hermansky-Pudlak syndrome 6. Orthologous to human HPS6 (HPS6 biogenesis of lysosomal organelles complex 2 subunit 3). [provided by Alliance of Genome Resources, Apr 2022]