Cox15 - cytochrome c oxidase assembly homolog COX15

Predicted to enable molecular adaptor activity and oxidoreductase activity, acting on NAD(P)H, heme protein as acceptor. Predicted to be involved in heme A biosynthetic process and respiratory chain complex IV assembly. Predicted to act upstream of with a positive effect on proton transmembrane transport. Predicted to be located in mitochondrion and nucleoplasm. Predicted to be part of cytochrome complex. Predicted to be active in mitochondrial inner membrane. Human ortholog(s) of this gene implicated in Leigh disease; fatal infantile cardioencephalomyopathy due to cytochrome c oxidase deficiency 2; and hypertrophic cardiomyopathy. Orthologous to human COX15 (cytochrome c oxidase assembly homolog COX15). [provided by Alliance of Genome Resources, Apr 2022]