Lama2 - laminin subunit alpha 2

Predicted to be an extracellular matrix structural constituent. Involved in Schwann cell differentiation. Located in basement membrane and dendritic spine. Biomarker of renovascular hypertension. Human ortholog(s) of this gene implicated in autosomal recessive limb-girdle muscular dystrophy; congenital merosin-deficient muscular dystrophy 1A; muscular dystrophy; and myopia. Orthologous to human LAMA2 (laminin subunit alpha 2). [provided by Alliance of Genome Resources, Apr 2022]