Fermt3 - FERM domain containing kindlin 3

Predicted to enable integrin binding activity. Predicted to be involved in several processes, including integrin activation; integrin-mediated signaling pathway; and platelet aggregation. Predicted to be located in podosome. Predicted to be active in cell-substrate junction. Biomarker of ovarian cancer. Human ortholog(s) of this gene implicated in leukocyte adhesion deficiency 1 and leukocyte adhesion deficiency 3. Orthologous to human FERMT3 (FERM domain containing kindlin 3). [provided by Alliance of Genome Resources, Apr 2022]