Map3k11 - mitogen-activated protein kinase kinase kinase 11
Alias:
Mlk3
RHOE
Mlk-3
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Basic Information
Sequence Homology
Transcripts & Proteins
Gene Expression
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Related Mouse Models
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Enables ATP binding activity; JUN kinase kinase kinase activity; and enzyme binding activity. Involved in several processes, including JNK cascade; positive regulation of JNK cascade; and positive regulation of neuron apoptotic process. Predicted to be located in microtubule. Predicted to be active in centrosome. Orthologous to human MAP3K11 (mitogen-activated protein kinase kinase kinase 11). [provided by Alliance of Genome Resources, Apr 2022]