Predicted to enable ubiquitin protein ligase activity. Predicted to be involved in protein K63-linked ubiquitination. Predicted to act upstream of or within defense response to Gram-negative bacterium; negative regulation of macromolecule metabolic process; and regulation of signal transduction. Orthologous to human PELI3 (pellino E3 ubiquitin protein ligase family member 3). [provided by Alliance of Genome Resources, Apr 2022]