Sigirr - single Ig and TIR domain containing

Predicted to enable NAD+ nucleosidase activity. Predicted to be involved in acute-phase response; negative regulation of cytokine-mediated signaling pathway; and regulation of gene expression. Predicted to be located in membrane. Orthologous to human SIGIRR (single Ig and TIR domain containing). [provided by Alliance of Genome Resources, Apr 2022]