Setd1a - SET domain containing 1A, histone lysine methyltransferase

Predicted to enable beta-catenin binding activity and histone methyltransferase activity (H3-K4 specific). Predicted to be involved in several processes, including histone H3-K4 methylation; regulation of erythrocyte differentiation; and regulation of hematopoietic stem cell differentiation. Predicted to act upstream of or within histone H3-K4 methylation; positive regulation of cell population proliferation; and stem cell population maintenance. Predicted to be located in euchromatin and nuclear speck. Predicted to be part of Set1C/COMPASS complex. Orthologous to human SETD1A (SET domain containing 1A, histone lysine methyltransferase). [provided by Alliance of Genome Resources, Apr 2022]