Rgma - repulsive guidance molecule BMP co-receptor a

Predicted to enable coreceptor activity and transferrin receptor binding activity. Involved in negative regulation of axon regeneration; negative regulation of collateral sprouting; and positive regulation of neuron projection development. Located in neuron projection. Used to study middle cerebral artery infarction. Biomarker of middle cerebral artery infarction; sciatic neuropathy; and temporal lobe epilepsy. Human ortholog(s) of this gene implicated in multiple sclerosis. Orthologous to human RGMA (repulsive guidance molecule BMP co-receptor a). [provided by Alliance of Genome Resources, Apr 2022]